By Michael J. Hyde, James A. Herrick
Technology, rhetoric, and conversing in regards to the post-human future.
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Extra info for After the genome : a language for our biotechnological future
34 g A fter the Genome Following Up Some other characteristics of regenerative medicine interventions—best exemplified by the need for long-term follow-up—can potentially complicate what might otherwise seem like simple determinations. Once again, regenerative medicine is not unique in this regard; it is, instead, uniquely illuminative of a more pervasive challenge in translational research. ” Cell-based interventions may need long-term follow-up so that investigators can learn about patterns of bioaccumulation and their potential effects, such as insertional mutagenesis, as has been seen in some gene transfer research, or other tumorigenic effects, as may be seen when some types of stem cells are used.
They are likely to be asked to make a considerable commitment to the research path, without changing paths to pursue standard treatments if they get tired of waiting for functional regeneration. it is always true that research subjects may cease participation at any time, and it is also true that many research subjects are lost to follow-up. 81 fAith in science f 35 The Fuzzy Research–Treatment Distinction and the Therapeutic Misconception As hinted by the previous discussion, regenerative medicine research may, generally speaking, be especially vulnerable to the therapeutic misconception.
The ability to generate replacement tissues and organs in a laboratory setting without inducing many of the negative sequelae associated with conventional organ transplantation would be a giant leap forward in medical technology and health science standards. These techniques can be applied to just about every field of medicine, 28 g A fter the Genome providing therapeutic options for any number of mild to severe diseases. Despite these advances, there are still significant scientific hurdles that must be overcome before further translation from bench to bedside can proceed.
After the genome : a language for our biotechnological future by Michael J. Hyde, James A. Herrick